Multiomic Health

AI-enabled precision medicine for cardio-renal-metabolic disease

ABOUT.

MultiOmic Health has built a platform for discovering and developing life-changing precision medicines for age-related chronic multifactorial diseases where genetics alone cannot explain why numerous patients continue to progress despite being treated on standard of care.

Our initial focus is the cardio-renal-metabolic landscape, a group of closely-related conditions constituting the world’s costliest healthcare burden, consuming $2 trillion in global healthcare costs in 2019 (1.6 times more than cancer) and forecasted to exceed $5.5 trillion by 2040. Our first platform use case is chronic kidney disease (CKD).

Using our unique combination of deep longitudinal patient datasets, AI-enabled data science capabilities and experimental biology expertise, we identify patient subpopulations having their own distinct molecular-level disease drivers. Our precision medicine platform spawns new treatments for these patient subpopulations, whose clinical trials will be smaller and shorter while yielding higher success rates compared to historical programmes in this disease space.

We aim to transform the clinical landscape by aligning research & development approaches with the emerging treatment paradigm to deliver holistic care in cardio-renal-metabolic. We have started building a global CRM patient registry that will be capturing over 100,000 patients by 2028. Our long-term mission is to become the preeminent central knowledge engine in this space.

THE CRM SPACE

  • Affects >2 billion patients worldwide (many undiagnosed)
  • Multiple conditions | heart | kidney | diabetes | liver | obesity
  • Causes more deaths than cancer
  • Trial-and-error prescribing, multiple doctors involved
  • Symptom control drugs only, no cures
  • No treatments for many serious downstream complications

OUR FOCUS.

In the near term, our work is focused on developing precision therapeutics for chronic kidney disease, expanding into cardiorenal conditions and diabetic complications.

We are investigating the underlying disease biology of these complications at the molecular level, using multiple omics modalities integrated with longitudinal clinical phenotyping.

The resulting insights enable us to derive much more effective therapeutics and associated companion diagnostics optimised for specific patient subpopulations.

STATISTICS.

The Cardio-Renal-Metabolic (CRM) Disease Continuum

cause of death globally - CRM CONDITIONS ACCOUNT FOR 45% OF GLOBAL DEATHS
#
ADULTS EXHIBIT METABOLIC RISK FACTORS THAT CONTRIBUTE TO THE GLOBAL CRM DISEASE BURDEN
bn
OF GLOBAL HEALTHCARE SPENDING IS DIRECTED TOWARDS CRM CONDITIONS
%
GLOBAL HEALTHCARE COST BURDEN OF CRM CONDITIONS
$tn

please view sidebar for data sources

WHAT WE DO

GENERATING Pharma-ready precision medicine programS.

UNDERSTANDING CHRONIC DISEASE BIOLOGY

1.

Impact of our renal endotyping and patient-stratifying-models (PSM) when optimized and implemented as diagnostic products (SaMD, IVD)

2.

Impact of our patient-stratified renal drug targets with companion diagnostics (CDx) when implemented as precision medicines

Contact.

Want to be a part of our team?

Got a partnership in mind?

Get in touch with us and know more about how we are changing the face of healthcare.

THE COMPANY

Multiomic Health Limited is a registered UK company 

Company #13246608

ADDRESS

Epworth House 

25 City Road, Shoreditch, London, EC1Y 1AA

Connect
EMAIL US

info@multiomic.health