ABOUT.
MultiOmic Health has built a platform for discovering and developing life-changing precision medicines for age-related chronic multifactorial diseases where genetics alone cannot explain why numerous patients continue to progress despite being treated on standard of care.
Our initial focus is the cardio-renal-metabolic landscape, a group of closely-related conditions constituting the world’s costliest healthcare burden, consuming $2 trillion in global healthcare costs in 2019 (1.6 times more than cancer) and forecasted to exceed $5.5 trillion by 2040. Our first platform use case is chronic kidney disease (CKD).
Using our unique combination of deep longitudinal patient datasets, AI-enabled data science capabilities and experimental biology expertise, we identify patient subpopulations having their own distinct molecular-level disease drivers. Our precision medicine platform spawns new treatments for these patient subpopulations, whose clinical trials will be smaller and shorter while yielding higher success rates compared to historical programmes in this disease space.
We aim to transform the clinical landscape by aligning research & development approaches with the emerging treatment paradigm to deliver holistic care in cardio-renal-metabolic. We have started building a global CRM patient registry that will be capturing over 100,000 patients by 2028. Our long-term mission is to become the preeminent central knowledge engine in this space.
THE CRM SPACE
- Affects >2 billion patients worldwide (many undiagnosed)
- Multiple conditions | heart | kidney | diabetes | liver | obesity
- Causes more deaths than cancer
- Trial-and-error prescribing, multiple doctors involved
- Symptom control drugs only, no cures
- No treatments for many serious downstream complications
OUR FOCUS.
In the near term, our work is focused on developing precision therapeutics for chronic kidney disease, expanding into cardiorenal conditions and diabetic complications.
We are investigating the underlying disease biology of these complications at the molecular level, using multiple omics modalities integrated with longitudinal clinical phenotyping.
The resulting insights enable us to derive much more effective therapeutics and associated companion diagnostics optimised for specific patient subpopulations.
STATISTICS.
The Cardio-Renal-Metabolic (CRM) Disease Continuum
please view sidebar for data sources
UNDERSTANDING CHRONIC DISEASE BIOLOGY
IMPACT.
1.
Impact of our renal endotyping and patient-stratifying-models (PSM) when optimized and implemented as diagnostic products (SaMD, IVD)
2.
Impact of our patient-stratified renal drug targets with companion diagnostics (CDx) when implemented as precision medicines
Contact.
Want to be a part of our team?
Got a partnership in mind?
Get in touch with us and know more about how we are changing the face of healthcare.
Multiomic Health Limited is a registered UK company
Company #13246608
Epworth House
25 City Road, Shoreditch, London, EC1Y 1AA
info@multiomic.health
